Alkaptonuria: a disease with dark brown urine

Alkaptonuria: a disease with dark brown urine.

Does Your Patient’s Urine Turns Dark? Alkaptonuria and Low Back Ache: A Literature Review

INTRODUCTION Alkaptonuria is a very rare inborn error of amino acid metabolism due to deficient homogentisic acid (HGA) oxidase enzyme leading to accumulation of HGA in plasma, cartilage, other tissues of human body and its excretion in urine. It has both systemic and peripheral signs and symptoms. Though low back is a common symptom of alkaptonuria but, in the absence of ochronosis it is rare....

Structuring Racist Ideologies in Stephen Crane’s “A Dark Brown Dog”: A Critical Discourse Analysis

This paper deals with the study of how racist ideologies are constructed in Crane’s “A Dark Brown Dog” using the CDA framework. Benefitting from the approaching between literature and linguistics, it focuses on the linguistic examination of the (re)construction of whiteness and blackness based on the assumption that racism is: a social, a discursive, and an ideological construct. This tri-dimen...

Alkaptonuria.

Alkaptonuria (AKU) is a rare disorder of autosomal recessive inheritance. It is caused by a mutation in a gene that results in the accumulation of homogentisic acid (HGA). Characteristically, the excess HGA means sufferers pass dark urine, which upon standing turns black. This is a feature present from birth. Over time patients develop other manifestations of AKU, due to deposition of HGA in co...

Alkaptonuria: A case report

Alkaptonuria is a rare inborn error of metabolism with autosomal recessive inheritance with a mutation in homogentisate 1,2-dioxygenase. It results in accumulation of homogentisic acid in connective tissues (ochronosis). Most common ocular manifestations are bluish-black discoloration of the conjunctiva, cornea, and sclera. In this case report, a 39-year-old Indian male patient with additional ...